Cubist Will Present at the Jefferies & Co. 2nd Annual Healthcare Conference on June 25th, 2008

Lexington, MA, May 30, 2008 -- Cubist Pharmaceuticals, Inc. (NASDAQ: CBST) today announced that Mike Bonney, President and CEO will present on Wednesday, June 25th at10:45 A.M. EDT, at the Jefferies & Co 2nd Annual Healthcare Conference being held at the Mandarin Oriental in New York City. This presentation will include discussion of the company's business activities, financial outlook, and current news.

A live webcast of the presentation will be accessible through Cubist's website at www.cubist.com in the Investor Relations Conference Calendar section. The webcast will be available on Cubist's website for a period of 90 days after the presentations.

About Cubist
Cubist Pharmaceuticals, Inc. is a biopharmaceutical company focused on the research, development, and commercialization of pharmaceutical products that address unmet medical needs in the acute care environment. In the U.S., Cubist markets CUBICIN® (daptomycin for injection), the first antibiotic in a new class of anti-infectives called lipopeptides. The Cubist product pipeline includes DX-88 (ecallantide), a recombinant human protein in Phase II clinical trials for the prevention of blood loss during cardiothoracic surgery, and pre-clinical programs that address unmet medical needs in Gram-positive infections, Gram-negative infections, CDAD (Clostridium difficile-associated diarrhea), and HCV (Hepatitis C infections). Cubist is headquartered in Lexington, MA. Additional information can be found at Cubist's web site at www.cubist.com.

Cubist and CUBICIN are registered trademarks of Cubist Pharmaceuticals, Inc.

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