Our 5 Year Goals / Building Blocks of Growth

Cubist Pharmaceuticals, Inc. is a biopharmaceutical company focused on the research, development, and commercialization of pharmaceutical products that address unmet medical needs in the acute care environment.

Our Strategy

In June, 2012, Cubist announced the Company’s five-year strategic aspirations — Building Blocks of Growth. The Company’s five-year roadmap, including goals for top- and bottom-line growth, future pipeline developments, and cultural elements will position Cubist to deliver long-term, sustainable growth. Cubist has established itself as a global leader in the acute care/hospital environment. Our Building Blocks of Growth will help the company build on this momentum as we look to deliver important new medicines for patients and drive long-term value for our customers and shareholders. The Building Blocks of Growth reflects what sets Cubist apart and will help us sharpen our organizational focus through 2017.

Our Pipeline

Acute care is the space where we work and invest. In the U.S., Cubist markets CUBICIN^® (daptomycin for injection), the first antibiotic in a class of anti-infectives called lipopeptides, and ENTEREG^® (alvimopan), the first and only FDA-approved therapy to accelerate the time to upper and lower gastrointestinal recovery following partial large or small bowel resection surgery with primary anastomosis. Cubist also has an agreement with Optimer Pharmaceuticals, Inc. to co-promote Optimer's drug, DIFICID^™ (fidaxomicin), in the U.S. as a treatment of Clostridium difficile-associated diarrhea (CDAD). Cubist's clinical product pipeline currently consists of a Phase 3 program focused on the development of a novel cephalosporin to address certain serious infections caused by multi-drug resistant (MDR) Gram-negative organisms, a Phase 3 program for the treatment of CDAD, and a Phase 3 program for the treatment of chronic opioid induced constipation (OIC). Cubist also is working on several pre-clinical programs being developed to address areas of significant medical needs. These include therapies to treat various serious bacterial infections and agents to treat acute pain.

Cubist is headquartered in Lexington, MA and employs approximately 780 people. 2012 Total net revenues grew 23% to $926.4 million compared to $754.0 million in 2011.

Our History

Founded in 1992, Cubist has maintained its focus on becoming a leader in the discovery, development and commercialization of novel acute care therapies for use in hospitals and other acute care environments.

Cubist completed its initial public offering (IPO) in 1996, and its shares are listed on NASDAQ (ticker symbol: CBST). In 1997, at a time when most pharmaceutical companies had abandoned discovery and development of antibiotics, Cubist in-licensed daptomycin, a first-in-class cyclic lipopeptide antibiotic drug candidate, originally discovered by scientists at Eli Lilly, which had discontinued its work on daptomycin as a drug candidate. Based on a breakthrough by Cubist scientists, Cubist resumed human trials with daptomycin in I.V. form, and the drug was approved by the FDA in 2003 as CUBICIN for the treatment of complicated skin and skin structure infections caused by certain gram-positive organisms. In 2006, the FDA approved an expanded U.S. label for CUBICIN for the treatment of S. aureus bloodstream infections (bacteremia), including right-sided infective endocarditis caused by MRSA and MSSA. The approval was based on results of the company's landmark Phase 3 trial studying the treatment of S. aureus bloodstream infections, including infective endocarditis. Today, we partner with other pharmaceutical companies to make CUBICIN available outside the United States in more than 70 countries, and the list continues to grow.

In December 2011, through its acquisition of Adolor Corporation, Cubist acquired rights to Adolor's commercialized product ENTEREG and its lead development candidate CB-5945, among other assets.

Click here for more information on Cubist's Pipeline.